Metacarpophalangeal pattern profile analysis in Sotos and Marfan syndrome
β Scribed by Dijkstra, P. F. ;Cole, T. R. P. ;Oorthuys, J. W. E. ;Venema, H. W. ;Oosting, J. ;Nocker, R. E. T.
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 490 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0148-7299
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## Marfan syndrome (MFS) is an autosomal dominant trait due to mutations in the fibrillin gene (FBN1). The MFS expressivity is variable, and its diagnosis relies completely on clinical criteria. Atypical cases and Marfan-like (marfanoid) clinical presentations are commonly found. The metacarpophal
## Metacarpophalangeal pattern (MCPP) analysis is an application of an anthropometric technique that provides a quantitative assessment of the amount and direction of abnormality in the hand skeleton. MCPP analysis was undertaken on 15 individuals (9 males, 6 females) with Noonan syndrome ranging i