The effects of aging on activation of metabotropic glutamate (mGlu) receptors were studied in the CA1 field of hippocampal slices from young (3-to 4-month-old) and aged (24-to 27-month-old) Sprague-Dawley rats with the use of ex vivo electrophysiological recording techniques. The depolarization of m
Metabotropic Glutamate Receptors Inhibiting Excitatory Synapses in the CA1 Area of Rat Hippocampus
✍ Scribed by Olivier Manzoni; Joël Bockaert
- Book ID
- 109017121
- Publisher
- John Wiley and Sons
- Year
- 1995
- Tongue
- English
- Weight
- 565 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0953-816X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract In the hippocampal CA1 region, metabotropic glutamate subtype 1 (mGluR1) receptors have been implicated in a variety of physiological responses to glutamate, which include modulation of synaptic transmission and plasticity, as well as neuronal excitability and synchronization. The mGluR
Low frequency-induced short-term synaptic plasticity was investigated in hippocampal slices with 60-electrode recording array. Remarkably, the application of low-frequency stimulation (1 Hz) for a short duration (3-5 min) resulted in the induction of a slow-onset longterm potentiation (LTP) in the i