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Metabotropic glutamate receptor agonists inhibit endogenous glutamate release from rat striatal synaptosomes

✍ Scribed by Stephen J. East; Michael P. Hill; Jonathan M. Brotchie


Book ID
115890154
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
412 KB
Volume
277
Category
Article
ISSN
0014-2999

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Astrocytes are thought to control extracellular glutamate concentrations ([Glu] o ) in the brain, thereby protecting neurons from excitotoxic injury. We investigated the effects of metabotropic glutamate receptor (mGluR) agonists on glutamate transport and [Glu] o in primary hippocampal astrocytic c