𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Metabolites of probenecid. Chemical, physical, and pharmacological studies

✍ Scribed by Israili, Z. H.; Perel, J. M.; Cunningham, R. F.; Dayton, P. G.; Yu, T. F.; Gutman, A. B.; Long, K. R.; Long, R. C.; Goldstein, J. H.

Book ID
121272082
Publisher
American Chemical Society
Year
1972
Tongue
English
Weight
742 KB
Volume
15
Category
Article
ISSN
0022-2623

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Pharmacological and biochemical studies
Pharmacological and biochemical studies with three metabolites of nomifensine
✍ H. Kruse; I. Hoffmann; H. J. Gerhards; M. Leven; U. Schacht πŸ“‚ Article πŸ“… 1977 πŸ› Springer 🌐 English βš– 571 KB

Three major metabolites (M1, M2, M3) of nomifensine (8-amino-1,2,3,4-tetrahydro-2-methyl-4-phenyl-isoquinoline) are formed by hydroxylation and methoxylation of the phenyl ring. They were compared with nomifensine 1. in various psychopharmacological tests in vivo, carried out in mice after oral or i

Cerebrospinal fluid cyclic AMP and acid
Cerebrospinal fluid cyclic AMP and acid monoamine metabolites following probenecid: Studies in psychiatric patients
✍ Malcolm B. Bowers; Robert E. Study πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 536 KB

At probenecid levels greater than 10 ~tg/ml, CSF cAMP was independent of CSF probenecid concentration. At these levels of probenecid, cAMP transport out of CSF is probably maximally blocked and cAMP levels reflect cAMP release into CSF. CSF cAMP was significantly higher in RDC-diagnosed schizophreni