✦ LIBER ✦

Metabolites in ventricular cerebrospinal fluid detected by proton magnetic resonance spectroscopic imaging

✍ Scribed by Lidia M. Nagae-Poetscher; Michael McMahon; Nancy Braverman; William T. Lawrie Jr.; Ali Fatemi; Mahaveer Degaonkar; Alena Horská; Martin G. Pomper; Vaddapuram P. Chacko; Peter B. Barker

Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 358 KB
Volume: 20
Category: Article
ISSN: 1053-1807
DOI: 10.1002/jmri.20128

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✦ Synopsis

Abstract

Normally, ventricular cerebrospinal fluid (CSF) contains low levels of all metabolite signals on proton magnetic resonance spectroscopic imaging (MRSI). We present here three cases (two with seizure disorders, one with a central nervous system lymphoma) who presented with unusually elevated CSF signals on MRSI. Based on chemical shifts and in vitro studies (in one case), the signals were assigned to propan‐1,2‐diol (PD), acetone, and lactate, respectively. These compounds were either exclusively, or more readily, detected in CSF than in brain. Proton MRSI conveniently screens both brain and CSF for abnormal metabolism simultaneously. J. Magn. Reson. Imaging 2004;20:496–500. © 2004 Wiley‐Liss, Inc.

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