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Metabolites and analogs of 1α,25-dihydroxyvitamin D3: evaluation of actions in bone

✍ Scribed by Sudha Kadiyala; Shizuka Nagaba; Kazuhiro Takeuchi; Shigefume Yukihiro; Weiping Qiu; Sharon T Eyes; Milan R Uskokovic; Gary H Posner; G.Satyanarayana Reddy; Sandra E Guggino

Book ID: 117213300
Publisher: Elsevier Science
Year: 2001
Tongue: English
Weight: 231 KB
Volume: 66
Category: Article
ISSN: 0039-128X
DOI: 10.1016/s0039-128x(00)00167-7

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In this communication we describe the synthesis of \(1 \alpha, 25\)-dihydroxyvitamin \(\mathrm{D}_{3}\) - \(3 \beta\)-bromoacetate \(\left[1,25(\mathrm{OH})_{2}-\mathrm{BE}\right]\), an analog of \(1 \alpha, 25\)-dihydroxyvitamin \(\mathrm{D}_{3}\left[1,25(\mathrm{OH})_{2} \mathrm{D}_{3}\right]\), a