Metabolite Safety in Drug Development

✍ Scribed by Suzanne L. Iverson, Dennis A. Smith

Publisher: Wiley
Year: 2016
Tongue: English
Leaves: 318
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

A reference on drug metabolism and metabolite safety in the development phase, this book reviews the analytical techniques and experimental designs critical for metabolite studies. It features case studies of lessons learned and real world examples, along with regulatory perspectives from the US FDA and EMA.

•   Reviews the analytical techniques and experimental designs critical for metabolite studies
•   Covers methods including chirality, species differences, mass spectrometry, radiolabels, and in vitro / in vivo correlation
•   Discusses target pharmacology, in vitro systems aligned to toxicity tests, and drug-drug interactions
•   Includes perspectives from authors with firsthand involvement in industry and the study of drug metabolites, including viewpoints that have influenced regulatory guidelines

✦ Subjects

Analytic;Chemistry;Science & Math;Industrial & Technical;Chemistry;Science & Math;Pharmacology;Cardiovascular;Chemistry;Clinical;Drug Delivery Systems;Drug Guides;For Nurses;For Veterinarians;Molecular;Neuropsychopharmacology;Pain Medicine;Pharmacodynamics;Pharmacy;Product Development;Reference;Toxicology;Pharmacology;Basic Sciences;Medicine;Medicine & Health Sciences;New, Used & Rental Textbooks;Specialty Boutique;Chemistry;Science & Mathematics;New, Used & Rental Textbooks;Specialty Boutique

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