Metabolism ofd(+)-carnitine byEscherichia coli

✍ Scribed by H. Jung; H.-P. Kleber

• Book ID: 104651091
• Publisher: Springer
• Year: 1991
• Tongue: English
• Weight: 232 KB
• Volume: 35
• Category: Article
• ISSN: 1432-0614
• DOI: 10.1007/bf00172731

✦ Synopsis

Escherichia coli 044 K74 grown u n d e r anaerobic c o n d i t i o n s in the presence o f L ( --) -c a r n i t i n e is able to convert D ( + ) -c a r n i t i n e into the L( --)-enantiomer. This activity is r e p r e s s e d by electron acceptors such as o x y g e n a n d nitrate as well as b y glucose. D ( + ) -C a rnitine shows no effect on the i n d u c t i o n or r e p r e s s i o n o f the c o r r e s p o n d i n g e n z y m e or enzyme system. Resting cells o f E. coli 044 K74 were used for the f o r m a t i o n o f L ( --) -c a r n i t i n e from D( + )-carnitine. The m a x i m u m obt a i n e d yield was 50%. 7 -B u t y r o b e t a i n e was f o r m e d as a b y -p r o d u c t .