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Metabolism of (−)-trans-(3R,4R)-dihydroxy-3,4-dihydrochrysene to diol epoxides by liver microsomes

✍ Scribed by Kamlesh P. Vyas; Haruhiko Yagi; Wayne Levin; Allan H. Conney; Donald M. Jerina


Book ID
118315552
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
486 KB
Volume
98
Category
Article
ISSN
0006-291X

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Metabolic Transformation of (3R, 4R)-Δ1(
✍ Michael Binder; Uwe Barlage 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 German ⚖ 699 KB

## Abstract The metabolism of the non‐psychotropic cannabinoid (3__R__, 4__R__)Δ^1(7)^‐tetrahydrocannabinol (**1**) (=Δ ^1(7)^‐THC) was investigated in a rat liver microsomal preparation. The metabolites obtained from the incubation mixture were separated, purified and identified by ^1^H‐NMR. spect