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Metabolism of the Chemoprotective Agent Diallyl Sulfide to Glutathione Conjugates in Rats

✍ Scribed by Jin, Lixia; Baillie, Thomas A.

Book ID
127228873
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
346 KB
Volume
10
Category
Article
ISSN
0893-228X

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The relation between the rate of glutathione (GSH) conjugation and hepatic GSH content was studied in the rat in uiuo and the in situ single-pass-perfused rat liver preparation with bromosulfophthalein (BSP) as the model substrate. The biliary excretion of the BSP-GSH conjugate and the hepatic GSH c