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Metabolism of nitrosamines and aflatoxin B1 by hamster liver CYP2A enzymes

✍ Scribed by Päivi Pelkonen; Gordon M. Kirby; Christopher P. Wild; Helmut Bartsch; Matti A. Lang


Book ID
113137814
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
538 KB
Volume
93
Category
Article
ISSN
0009-2797

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We have studied the activation of aflatoxin B, by hamster liver microsomes and purified hamster cytochrome P-450 isozymes using a umu mutagen test. The hamster liver microsomes or S-9 fractions were much more active than rat liver microsomes or s-9 fractions in the activation of umu gene expression