Metabolism of Nicotine to (+)-γ-(3-Pyridyl)-γ-methylaminobutyric Acid 1
✍ Scribed by McKennis, Herbert; Turnbull, Lennox B.; Bowman, Edward R.
- Book ID
- 126136800
- Publisher
- American Chemical Society
- Year
- 1958
- Tongue
- English
- Weight
- 536 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
There are numerous possible gamma-amino acids with different degrees of substitution and with various constitutions and configurations. Of these the gamma4- and the like- and unlike-gamma(2,4)-amino acids have been previously used as building blocks in gamma-peptides. The synthesis of gamma2-, gamma
g-Hydroxybutyric acid (GHB) is a drug of abuse. Literature studies showed that d-glucuronate acts as an oxidative stimulator of GHB metabolism following in vivo GHB tracer doses. The present proof-of-concept study investigates if d-glucuronate enhances GHB metabolism and inhibits blood-brain barrier