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Metabolism of hemoglobin-vesicles (artificial oxygen carriers) and their influence on organ functions in a rat model

โœ Scribed by Hiromi Sakai; Hirohisa Horinouchi; Yohei Masada; Shinji Takeoka; Eiji Ikeda; Masuhiko Takaori; Koichi Kobayashi; Eishun Tsuchida

Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
301 KB
Volume
25
Category
Article
ISSN
0142-9612

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## Abstract Hemoglobin vesicles (HbVs), liposomal oxygen carriers containing human hemoglobin, are candidates for development as clinically useful blood substitutes. Although HbVs are shown to distribute transiently into the bone marrow in animal models, the influence of HbVs on human hematopoietic