Metabolism of glycosaminoglycans in cultured normal and abnormal human fibroblasts
β Scribed by Nicola Di Ferrante; Patricia V. Donnelly; Giovanni Neri
- Book ID
- 115766027
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- English
- Weight
- 532 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0006-2944
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## Abstract A morphologically detectable cell coat, composed of glycoprotein, glycolipid, and glycosaminoglycan, is present on the external surface of most vertebrate cells. We have invetigated the composition and organization of glycosaminoglycans in the cell coat of cultured human embryo fibrobla
Glycosaminoglycans are polysaccharides involved in epithelial-mesenchymal interaction and cell differentiation and provide a meshwork which is essential to maintain a proper intercellular milieu. The development of embryonic organs can be accompanied by alterations in the glycosaminoglycan pattern.