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Metabolism of exogenous 4- and 2-hydroxyestradiol in the human male

✍ Scribed by G. Emons; G.R. Merriam; D. Pfeiffer; D.L. Loriaux; P. Ball; R. Knuppen

Book ID
116006376
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
435 KB
Volume
28
Category
Article
ISSN
0022-4731

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## Abstract An elevated incidence of breast cancer in women has been associated with prolonged exposure to high levels of estrogens. Our laboratory demonstrated that treatment of the immortalized human breast epithelial cells MCF‐10F with 17β‐estradiol (E~2~), 4‐hydroxyestradiol (4‐OHE~2~) or 2‐hyd