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Metabolism of benzo[a]pyrene by mouse brain microsomes during perinatal development

✍ Scribed by Patricia Rouet; P.M. Dansette; A. Weston; C. Frayssinet

Book ID
113136732
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
268 KB
Volume
48
Category
Article
ISSN
0009-2797

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## Abstract A rat liver microsome‐mediated bacterial mutagenicity test showed 9‐hydroxybenzo (__a__) pyrene to be significantly more effective as a pre‐mutagen than benzo (__a__) pyrene. Experiments measuring the ability of these compounds to be metabolically activated to moieties that alky late ex