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Metabolism of anethole. II. Influence of dose size on the route of metabolism of trans-anethole in the rat and mouse

✍ Scribed by Sangster, S.A.; Caldwell, J.; Smith, R.L.

Book ID: 123320802
Publisher: Elsevier Science
Year: 1984
Tongue: English
Weight: 546 KB
Volume: 22
Category: Article
ISSN: 0278-6915
DOI: 10.1016/0278-6915(84)90197-2

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## Abstract Racemic __trans__‐anethole epoxide [1‐(4′‐methoxyphenyl)‐propane‐1,2‐oxide] was incubated with water, buffers, and rat liver microsomes and cytosol and the stereochemistry of the diols produced was determined by HPLC as their dicamphanyl esters. The diol metabolites were isolated by HPL