Identification of phenylbutyrylglutamine
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Blandine Comte; Takhar Kasumov; Bradley A. Pierce; Michelle A. Puchowicz; Mary-E
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Article
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2002
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John Wiley and Sons
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English
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Phenylbutyrate is used in humans for treating inborn errors of ureagenesis, certain forms of cancer, cystic fibrosis and thalassemia. The known metabolism of phenylbutyrate leads to phenylacetylglutamine, which is excreted in urine. We have identified phenylbutyrylglutamine as a new metabolite of ph