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Metabolism of 5-hydroxytryptophan in isolated perfused liver from normal and x-irradiated rats

✍ Scribed by Gerber, G. B. ;Deroo, J.

Publisher
Springer-Verlag
Year
1971
Weight
518 KB
Volume
8
Category
Article
ISSN
0006-3517

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The liver glutathione content was measured after oral administration of 1,1-dichloroethylene (vinylidene chloride = VDC; dissolved in olive oil) and its significance for the metabolism and hepatotoxicity of VDC was investigated. After treatment with 1000 mg/kg VDC p.o., glutathione decreased to 33%