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Metabolism of 5-hydroxy-4-keto-valeric acid in the rat

✍ Scribed by Feng K. Wang; Jürgen Koch; E.L.R. Stokstad

Book ID
118852172
Publisher
Elsevier Science
Year
1970
Tongue
English
Weight
408 KB
Volume
40
Category
Article
ISSN
0006-291X

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✍ Rudolf Tschesche; Wolfgang Wirth 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 265 KB

## Abstract 5‐Hydroxy‐4‐keto [4‐^14^C]valeric acid was prepared from 5‐amino [4‐^14^C]levulinic acid. The synthesis of 5‐hydroxy‐4‐keto [1‐^14^C]valeric acid (**4**) was achieved by Grignard reaction of 1‐benzyloxy‐4‐bromo‐2‐butanone ethylene acetal (**1**) with ^14^CO~2~ and subsequent removal of