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Metabolism of 1,2-dibromoethane in the human fetal liver

โœ Scribed by Arun P. Kulkarni; John Edwards; Ira S. Richards


Book ID
116128878
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
481 KB
Volume
23
Category
Article
ISSN
0306-3623

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The nematocide, grain fumigant, and gasoline additive 1,2-dibromoethane (DBE) is both a cellular and a genetic toxin that is metabolically activated in rats and mice by mixed function oxidases (MFO) as well as glutathione S-transferases (GST). The purpose of this study was to determine whether DBE i