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Metabolism: New role of insulin and IGF-1 receptors in the expression of imprinted genes and microRNAs

Book ID
126662496
Publisher
Nature Publishing Group
Year
2014
Tongue
English
Weight
529 KB
Volume
10
Category
Article
ISSN
1759-5029

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## Background and Objectives: We have previously shown that insulin-like growth factor (IGF)-responsive murine sarcomas demonstrate inhibition of local and metastatic disease growth when implanted in an IGF-deficient host animal. In this experiment, we tested whether IGF receptor (IGF-R) and ligan