Metabolism, excretion and toxicology of trichloroethylene after inhalation
β Scribed by Georg Kimmerle; Anneliese Eben
- Publisher
- Springer-Verlag
- Year
- 1973
- Tongue
- English
- Weight
- 609 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0340-5761
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π SIMILAR VOLUMES
## Abstract The neurobehavioural effects of trichloroethylene (TCE) were studied in rats following administration of the solvent orally (350, 700 and 1400 ppm in drinking water for 90 days) and through inhalation (376 ppm for 4 h a day, 5 days per week for 180 days). Various aspects of spontaneous
The inhalation exposure of adult male rats to 7.9 mumol/l (200 ppm) of trichloroethylene for 4 days 6 h each day led to an accumulation of the solvent in the perirenal fat 17 h after the last exposure. Exposures to 20 mumol/l (500 ppm) of 1,1,1-trichloroethane caused similar accumulation. The latter