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Metabolism and physiologically based pharmacokinetic modeling of flumioxazin in pregnant animals

✍ Scribed by Takaku, Tomoyuki; Nagahori, Hirohisa; Sogame, Yoshihisa


Book ID
122282376
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
786 KB
Volume
277
Category
Article
ISSN
0041-008X

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πŸ“œ SIMILAR VOLUMES


Physiologically based pharmacokinetic mo
✍ Kannan Krishnan; Lee C.B. Crouse; Matthew A. Bazar; Michael A. Major; Gunda Redd πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 369 KB

## Abstract A physiologically based pharmacokinetic (PBPK) model for simulating the kinetics of cyclotrimethylene trinitramine (RDX) in male rats was developed. The model consisted of five compartments interconnected by systemic circulation. The tissue uptake of RDX was described as a perfusion‐lim