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Metabolism and pharmacokinetics of [14C]-deoxyfructosylserotonin creatinine sulfate administered orally and intravenously to rats and mice

โœ Scribed by J. -E. Germond; E. Gremaud; U. Richli; R. Badoud; J. -M. Aeschlimann; M. J. Arnaud


Book ID
113005963
Publisher
Springer-Verlag
Year
1993
Tongue
English
Weight
900 KB
Volume
18
Category
Article
ISSN
0378-7966

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The single-dose pharmacokinetics and bioavailability of three ketoconazole formulations were evaluated using HPLC in five healthy human volunteers and six male mongrel dogs. The human volunteers received 400 mg PO of ketoconazole as tablet (Ktab) and solution (K-,) formulations. The dogs received 40