35S-Furosemide was administered to beagle dogs and rhesus monkeys in an oral solution on a single and a 20 repeated 5-mg/kg/day dosing regimen. Following the single dose, 25.0% (dogs) and 24.0% (monkeys) of the dose were excreted in the urine in 24 hr. TLC analysis demonstrated that both species had
Metabolism and excretion of normorphine in dogs
โ Scribed by S. Y. Yeh; R. L. McQuinn; H. A. Krebs; C. W. Gorodetzky
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 330 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3549
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Clindamycin hydrochloride, randomly labeled with tritium, was synthesized and used for animal metabolism studies. The drug was administered to rats (oral and intraperitoneal routes) and dogs (oral and intramuscular routes) at a dose of 50-150 mg./ kg. In both species, after the oral or parenteral dr
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