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Metabolism and energy requirements in pantothenate kinase-associated neurodegeneration

✍ Scribed by Williams, Sarah; Gregory, Allison; Hogarth, Penelope; Hayflick, Susan J.; Gillingham, Melanie B.


Book ID
123405569
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
231 KB
Volume
110
Category
Article
ISSN
1096-7192

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## Abstract Pantothenate kinase–associated neurodegeneration (PKAN) causes a progressive generalized dystonia which remains pharmacologically intractable. We performed bilateral internal globus pallidus stimulation in six patients with genetically confirmed PKAN who obtained a major and long‐lastin