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Metabolism and elimination of quinine in healthy volunteers

✍ Scribed by RajaaA. Mirghani; Urban Hellgren; Leif Bertilsson; LarsL. Gustafsson; Örjan Ericsson

Book ID
105920876
Publisher
Springer
Year
2003
Tongue
English
Weight
222 KB
Volume
59
Category
Article
ISSN
0031-6970

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Altered flecainide disposition in health
Altered flecainide disposition in healthy volunteers taking quinine
✍ A. Munafo; G. Reymond-Michel; J. Biollaz 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 572 KB

The pharmacokinetics of flecainide and its two sequential metabolites, both free and conjugated, its pharmacodynamics, and the influence of simultaneously administered quinine, have been studied in 10 healthy subjects. The study comprised two, 48-h open phases at an interval of 1 week. Flecainide ac