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Metabolism and distribution of 1-[14C]alprazolam in rats

โœ Scribed by William R. Banks; Hirokazu Yamakita; George A. Digenis

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
579 KB
Volume
81
Category
Article
ISSN
0022-3549

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The metabolism and disposition of [2,3-'4C]acrolein was studied in Sprague-Dawley rats after oral or intravenous dosing. Four groups of ten rats (five male and five female) were dosed with radiolabeled acrolein intravenously at 2.5 mg kg-' (Group 2), orally by gavage at 2.5 mg kg-I, either as a sing