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Metabolism and cholestatic effect of 3α-hydroxy-7ζ-methyl-5β-cholanoic acid

✍ Scribed by Mizuho Une; Erwin H. Mosbach; Bertram I. Cohen; Patricia May-Donath; Charles K. Mcsherry

Book ID: 112772494
Publisher: Springer-Verlag
Year: 1985
Tongue: English
Weight: 385 KB
Volume: 20
Category: Article
ISSN: 0024-4201
DOI: 10.1007/bf02534192

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## Abstract 3α‐Hydroxy‐7‐keto‐5β‐cholanic acid has been prepared from cholic acid by a route which allowed introduction of ^3^H into positions 11 and 12 of the steroid C ring. Labelling with ^14^C was done by halodecarboxylation and resynthesis of the carboxyl function with ^14^C cyanide. The conju