METABOLISM: Amylin and diabetes
✍ Scribed by Stephanie Amiel; JensO.L. Jo̸rgensen; JensS. Christiansen; Ann Logan; Bruce Arroll; Robert Beaglehole; Stephanie Amiel
- Book ID
- 119065888
- Publisher
- The Lancet
- Year
- 1993
- Tongue
- English
- Weight
- 319 KB
- Volume
- 341
- Category
- Article
- ISSN
- 0140-6736
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📜 SIMILAR VOLUMES
Since the discovery of the pancreatic islet hormone amylin in 1987, its metabolic effects have been investigated in a number of studies in animals and humans. Data from some early animal studies suggested that amylin might be associated with the development of insulin resistance, but other studies f
The 37-amino acid amylin, co-secreted from the pancreatic p cells with insulin in response to nutrient stimuli has actions in a number of tissues of metabolic interest. In muscle it opposes glycogen synthesis and activates glycogenolysis, an action likely to underly its stimulation of lactate flux.