Metabolic systems analysis to advance algal biotechnology
β Scribed by Brian J. Schmidt; Xiefan Lin-Schmidt; Austin Chamberlin; Kourosh Salehi-Ashtiani; Jason A. Papin
- Book ID
- 112012250
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 506 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1860-6768
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π SIMILAR VOLUMES
Based on a simplified model of a linear metabolic pathway (Kacser & Burns, 1973), and on the principles of Metabolic Control Analysis, an equation useful for predicting the maximum flux through a system after removing inhibitory feedback interaction is presented. The analysis shows that only when th
## Abstract When a metabolic system undergoes a transition between steady states, the lag or transition time of the system is determined by the aggregated lifetimes of the metabolite pools. This allows the transition time, and hence the temporal responsiveness of the system, to be estimated from a
Metabolic control analysis has provided experimental tools and a precise language to understand and to describe regulation and control quantitatively in complex, dynamic metabolic systems. The top-down approaches of control analysis reduce and simplify the experiments required to analyse: (1) the po