Metabolic syndrome and prostate cancer
โ Scribed by L. Michael Glode
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 50 KB
- Volume
- 112
- Category
- Article
- ISSN
- 0008-543X
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โฆ Synopsis
The metabolic syndrome (MetS) was first proposed as a clinical entity in 1988 and has been popularized by numerous health organizations as a way of identifying patients at increased risk for coronary heart disease or type II diabetes. The numerous definitions for MetS has made it somewhat difficult for practicing physicians to adopt a standard and then apply it to behavioral modification and/or pharmacologic therapy for their patients. In this issue of Cancer, Smith et al. performed a prospective analysis of some components of MetS in 26 men with locally advanced or recurrent prostate cancer who were treated with 1 year of leuprolide in addition to 1 month of bicalutamide at the time of the initiation of gonadotropinโreleasing hormone agonist therapy. Some differences between classic MetS and the androgen deprivation syndrome were demonstrated.
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