๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

METABOLIC STUDIES ON PSYCHOACTIVE DRUGS

โœ Scribed by C. Jelleff Carr


Book ID
114876924
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
630 KB
Volume
96
Category
Article
ISSN
0890-6564

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## Abstract ## Objective Variation in the activity of cytochrome P450 2D6 (CYP2D6) affects the pharmacokinetics and effectiveness of dextromethorphan (DM), because it controls the production of dextrorphan, an active metabolite, with higher affinity for the NMDA receptor than the parent compound.