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Metabolic studies of an orally active platinum anticancer drug by liquid chromatography-electrospray ionization mass spectrometry

✍ Scribed by G.K. Poon; F.I. Raynaud; P. Mistry; D.E. Odell; L.R. Kelland; K.R. Harrap; C.F.J. Barnard; B.A. Murrer

Book ID
107785636
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
408 KB
Volume
712
Category
Article
ISSN
1873-3778

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## Abstract The application of liquid chromatography/mass spectrometry (LC/MS) and LC/MS/MS with electrospray ionization to drug metabolism studies was investigated using S 9788 and various synthesized metabolic products as model compounds to assess the response characteristics with regard to compo