Metabolic Regulation of Ca2+ Release in Permeabilized Mammalian Skeletal Muscle Fibres
โ Scribed by Elena V. Isaevaand; Natalia Shirokova
- Book ID
- 110112171
- Publisher
- Cambridge University Press
- Year
- 2003
- Tongue
- English
- Weight
- 980 KB
- Volume
- 547
- Category
- Article
- ISSN
- 0022-3751
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Ca2+ release from skeletal sarcoplasmic reticulum (SR) could be regulated by at least three mechanisms: 1) Ca2+, 2) calmodulin, and 3) Ca2+/calmodulin-dependent phosphorylation. Bell-shaped Ca(2+)-dependence of Ca2+ release from both actively- and passively-loaded SR vesicles suggest that opening an