Metabolic products of microorganisms. 185. The anthraquinones of theAspergillus glaucusgroup. I. Occurrence, isolation, identification and antimicrobial activity

✍ Scribed by Heidrun Anke; Itham Kolthoum; Hans Zähner; Hartmut Laatsch

• Book ID: 104762408
• Publisher: Springer
• Year: 1980
• Tongue: English
• Weight: 722 KB
• Volume: 126
• Category: Article
• ISSN: 0302-8933
• DOI: 10.1007/bf00409924

✦ Synopsis

The occurrence of emodin, erythroglaucin, physcion, physcion-9-anthrone, questin, catenarin, and catenarin-8-methyl ether in different species of the Aspergillus glaucus group (genus Eurotium) was investigated. So far catenarin-8-methyl ether (1, 4, 6-trihydroxy-8-methoxy-3-methylanthraquinone) has not been described as a natural product; it was therefore given the name rubrocristin. The chemical and physical properties of rubrocristin are reported. In addition a new violet pigment (C16H1205) was isolated and characterized by its MS-, IR-and UV-spectra.

The antimicr0bial properties of all substances were examined in the agar diffusion assay. Gram-positive bacteria were the most sensitive organisms and catenarin was the most active naturally occurring substance. Synthetically obtained 1, 4, 6, 8-tetrahydroxyanthraquinone was slightly more active than catenarin, whereas rubrocristin showed no antibacterial activity.