𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Metabolic Fluxes and Metabolic Engineering

✍ Scribed by Gregory Stephanopoulos


Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
504 KB
Volume
1
Category
Article
ISSN
1096-7176

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Flux Estimation Using Isotopic Tracers:
✍ Joanne K. Kelleher πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 229 KB

Metabolic physiologists and metabolic engineers share the need to estimate flux. However, the physiologist often works with systems that do not maintain steady state for long. Many sites cannot be sampled, and calculating mass and isotopic balance for the entire system may not be feasible. To deal w

Metabolic Engineering through Cofactor M
✍ Ka-Yiu San; George N. Bennett; Susana J. Berrı́os-Rivera; Ravi V. Vadali; Yea-Ty πŸ“‚ Article πŸ“… 2002 πŸ› Elsevier Science 🌐 English βš– 215 KB

Applications of genetic engineering or metabolic engineering have increased in both academic and industrial institutions. Most current metabolic engineering studies have focused on enzyme levels and on the effect of the amplification, addition, or deletion of a particular pathway. Although it is gen

A MILP-Based Flux Alternative Generation
✍ C. Phalakornkule; S. Lee; T. Zhu; R. Koepsel; M.M. Ataai; I.E. Grossmann; M.M. D πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 276 KB

A mixed-integer linear program (MILP) is described that can enumerate all the ways fluxes can distribute in a metabolic network while still satisfying the same constraints and objective function. The multiple solutions can be used to (1) generate alternative flux scenarios that can account for limit

Toward Predicting Metabolic Fluxes in Me
✍ James C. Liao; Min-Kyu Oh πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 218 KB

Predicting metabolic fluxes of a genetically engineered organism is an important step toward rational pathway design. However, because of various regulatory mechanisms, which are complex, often ill-characterized, and sometimes undiscovered, predicting metabolic fluxes using kinetic simulation is dif

Metabolic engineering
✍ Gregory Stephanopoulos πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 15 KB