Physiological state multiplicity was observed in continuous cultures of the hybridoma cell line ATCC CRL-1606 cultivated in glutamine-limited steady state chemostats. At the same dilution rate (0.04 h -1 ), two physiologically different cultures were obtained which exhibited similar growth rates and
✦ LIBER ✦
Metabolic flux analysis of cultured hepatocytes exposed to plasma
✍ Scribed by Christina Chan; François Berthiaume; Kyongbum Lee; Martin L. Yarmush
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 209 KB
- Volume
- 81
- Category
- Article
- ISSN
- 0006-3592
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## KEY WORDS Allopurinol-analysis Oxypurinol-analysis Drug metabolism-in vitro Oxypurinol-pharmacokinetics EXPERIMENTAL ## Chemicals and reagents Allopurinol and oxypurinol, obtained from Burroughs Wellcome, Ltd. (LaSalle, Quebec), were dissolved in aqueous 0.1N HC1 at a concentration of