𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Metabolic fate of N,N-dimethyl-N′-(p-phenoxyphenyl)sulfamide in rat, dog, and human

✍ Scribed by F. F. Sun; J. E. Stafford

Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
503 KB
Volume
63
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Metabolic fate of N-γ-phenylpropyl-n-ben
Metabolic fate of N-γ-phenylpropyl-n-benzyloxy acetamide (w-1372) in rats, dogs, and monkeys
✍ Jerome Edelson; J. F. Douglas; B. J. Ludwig 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 English ⚖ 300 KB

The absorption, distribution, and metabolic fate of N-7-phenylpropyl-N-benzyloxy acetamide (W-1372) was studied in the rat, dog, and monkey. W-1372-14C was readily absorbed by all three species. Following an oral dose, peak blood levels of radioactivity were attained within 1 hr. in the monkey and i

p -HYDROXYMETHAMPHETAMINE ENANTIOMER PHA
p -HYDROXYMETHAMPHETAMINE ENANTIOMER PHARMACOKINETICS AND METABOLISM IN RATS: ABSENCE OF N-DEMETHYLATION
✍ A. HUTCHALEELAHA; M. MAYERSOHN 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 151 KB 👁 2 views

p-hydroxymethamphetamine (OHMAP) is one of the major metabolites of the widely abused drug methamphetamine (MAP). The demethylation of OHMAP to phydroxyamphetamine (OHAP) has been shown in vitro but has never been reported in vivo. The disposition kinetics as well as the metabolism of OHMAP was inve

Stereoselective metabolism of famprofazo
Stereoselective metabolism of famprofazone in humans: N-dealkylation and β-and p-hydroxylation
✍ Ho-Sang Shin 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 172 KB 👁 1 views

Following administration of famprofazone to humans, the stereoselective metabolism from the drug to its known metabolites (+,-)-ephedrine, (+,-)pseudoephedrine, (+,-)-norephedrine, (+,-)-norpseudoephedrine, (+,-)-p-hydroxyamphetamine, (+,-)-p-hydroxymethamphetamine, and (+,-)-p-hydroxynorephedrine w