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Metabolic fate of caudate nucleus dopamine

โœ Scribed by Piero F. Spano; Norton H. Neff


Book ID
118860060
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
376 KB
Volume
42
Category
Article
ISSN
0006-8993

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3H-GBR 12935 was used to label the digitonin-solubilized dopamine transporter from dog caudate nucleus. Specific binding to soluble fractions was observed in dog caudate but was absent in rat cerebellum. Binding to the solubilized transporter sites was saturable and of high affinity (Bmm = 2.57 -+ 0