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Metabolic evaluation of isolated porcine hepatocytes cultured in human and in pig plasma

โœ Scribed by A Donini; V Corno; A Risaliti; V Bonfreschi; V Vianello; C Gonano; G Anania; A Pasqualotto; O Belvedere; A Degrassi; F Bresadola

Book ID
118568566
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
154 KB
Volume
28
Category
Article
ISSN
0168-8278

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โœ Radim Kral; Lenka Skalova; Barbora Szotakova; Jakub Velik; Ladislava Schroterova ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› BioMed Central ๐ŸŒ English โš– 312 KB

## Background: Flobufen (f) is an original nonsteroidal anti-inflammatory drug with one center of chirality. 4-dihydroflobufen (dhf), compound with two chiral centers, is the main metabolite of f in microsomes and cytosol in all standard laboratory animals. this work describes the biotransformation