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Metabolic engineering of the nonmevalonate isopentenyl diphosphate synthesis pathway in Escherichia coli enhances lycopene production

โœ Scribed by Seon-Won Kim; J. D. Keasling


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
231 KB
Volume
72
Category
Article
ISSN
0006-3592

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## Abstract To increase expression of lycopene synthetic genes __crtE__, __crtB__, __crtI__, and __ipiHP1__, the four exogenous genes were cloned into a high copy pTrc99A vector with a strong __trc__ promoter. Recombinant __Escherichia__ __coli__ harboring pTโ€LYCm4 produced 17 mg/L of lycopene. The