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Metabolic effects of sustained activation of the GLP-1 receptor alone and in combination with background GIP receptor antagonism in high fat–fed mice

✍ Scribed by N. Irwin; P. L. McClean; K. Hunter; P. R. Flatt


Book ID
109044807
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
210 KB
Volume
11
Category
Article
ISSN
1462-8902

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## Abstract ## Background The two major incretin hormones, glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1) are being actively explored as anti‐diabetic agents because they lower blood glucose through multiple mechanisms. The rapid inactivation of GIP and GLP‐