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Metabolic effects of silibinin in the rat liver

✍ Scribed by Carina Parisoto Colturato; Rodrigo Polimeni Constantin; Antônio Sueiti Maeda Jr.; Renato Polimeni Constantin; Nair Seiko Yamamoto; Adelar Bracht; Emy Luiza Ishii-Iwamoto; Jorgete Constantin


Book ID
113518454
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
787 KB
Volume
195
Category
Article
ISSN
0009-2797

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## Abstract The action of carbenoxolone on hepatic energy metabolism was investigated in the perfused rat liver and isolated mitochondria. In perfused livers, carbenoxolone (200–300 μM) increased oxygen consumption, glucose production and glycolysis from endogenous glycogen. Gluconeogenesis from la