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Metabolic Detoxification Determines Species Differences in Coumarin-Induced Hepatotoxicity

โœ Scribed by Vassallo, J. D.


Book ID
121685901
Publisher
Oxford University Press
Year
2004
Tongue
English
Weight
175 KB
Volume
80
Category
Article
ISSN
1096-6080

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Coumarin (1,2-benzopyrone), a natural food con-nicity with rat liver S9. When liver S9 from chick stituent, prevents polycyclic aromatic hydrocarbon-embryos pretreated with coumarin was used for aflainduced neoplasms in rats and mice, but has not toxin B 1 bioactivation, mutant frequency and cytotox