## Abstract Two cytochrome P450 alleles, __CYP6A5__ and __CYP6A5v2__, were isolated from a pyrethroidβresistant house fly stain, ALHF. The two alleles shared 98% similarity in amino acid sequence. To understand the importance of these two alleles in resistance and examine the expression profile of
β¦ LIBER β¦
Metabolic detoxication and the kdr mutation in pyrethroid resistant house flies, Musca domestica (L.)
β Scribed by Nannan Liu; Julia W Pridgeon
- Book ID
- 114096799
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 196 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0048-3575
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The voltage-sensitive sodium channel is generally regarded as the primary target site of dichloro-diphenyl-trichloro-ethane (DDT) and pyrethroid insecticides, and has been implicated in the widely reported mechanism of nerve insensitivity to these compounds. This phenomenon is expressed as knockdown