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Metabolic consequences of DNA damage: Alteration in purine metabolism following poly(ADP ribosyl)ation in human T-lymphoblasts

✍ Scribed by Amos Cohen; Jerzy Barankiewicz


Book ID
115707423
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
550 KB
Volume
258
Category
Article
ISSN
0003-9861

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Effects of nicotinamide on NAD and poly
✍ Sims, James L. ;Berger, Sosamma J. ;Berger, Nathan A. πŸ“‚ Article πŸ“… 1981 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 483 KB

## Abstract The effect of nicotinamide on unscheduled DNA synthesis was studied in resting human lymphocytes. In cells treated with UV irradiation or with MNNG, nicotinamide caused a two‐fold stimulation of unscheduled DNA synthesis and retarded the rate of NAD^+^ lowering caused by these treatment