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Metabolic cholesterol depletion hinders cell-surface trafficking of the nicotinic acetylcholine receptor

✍ Scribed by M.F. Pediconi; C.E. Gallegos; E.B. de Los Santos; F.J. Barrantes

Book ID: 116786503
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 359 KB
Volume: 128
Category: Article
ISSN: 0306-4522
DOI: 10.1016/j.neuroscience.2004.06.007

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## Abstract The αM4 transmembrane domain of the nicotinic acetylcholine receptor (AChR) is flanked by two basic amino acids (His^408^ and Arg^429^) located at its cytoplasmic‐ and extracellular‐facing extremes, respectively, at the level of the phospholipid polar head regions of the postsynaptic me