𝔖 Bobbio Scriptorium
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Metabolic catastrophe as a means to cancer cell death

✍ Scribed by Jin, S.; DiPaola, R. S.; Mathew, R.; White, E.

Book ID
120180796
Publisher
The Company of Biologists Ltd
Year
2007
Tongue
English
Weight
335 KB
Volume
120
Category
Article
ISSN
0021-9533

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## Abstract DNA damage occurs in ischemia, excitotoxicity, inflammation, and other disorders that affect the central nervous system (CNS). Extensive DNA damage triggers cell death and in the mature CNS, this occurs primarily through activation of the poly(ADP‐ribose) polymerase‐1 (PARP‐1) cell deat